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How does DCA act in our body?
On this page you will get substantial information
about the essential mechanism of your DCA-based primary immunity
response.
> The discovery of our immunity
vitamin
> The role of DCA in our immune
defence
> Stages of immune deficiency
The discovery of our Immunity Vitamin
DCA stands for Deoxy Cholic Acid. It is known for about 100 years
as a substance occurring naturally in the body. DCA is classified
in the medical category of secondary bile acids. What we know of
the bile acids is their big role in fat digestion. In traditional
western medicine no further important roles seem to have an impact
on the nature of bile acids. But if we look a little bit closer
on DCA, we discover that it has a completely different physiological
behaviour in our body than the other secondary bile acids. That
is only logical, if we allow the idea that deoxycholic acid has
a totally different (second) function in our body than it was known
till today.
The main function of DCA was discovered between 1967 and 1968 by
a group of Czech scientists under the leadership of Dr. Bohuslav
Vlcek. It is due to him, that we have now this profound knowledge
about the function of our initial immune defence. Back in the late
sixties, Dr. Vlcek was the one of the heads of the chemistry department
of the venerable Karls University in Prague, Czech Republic, and
the designated successor of the Nobel prize winner Prof. Hérovský.
The investigations of this scientist and his group were the start
up of a new understanding of how our unspecific immune system works.
The main discovery lies in the fact, that DCA´s main function is
the role of a immunomodulator, that controls the activation of our
unspecific immune system. Later a second function of DCA was obvious
as a “global player” in the hormonal balance of our body.
Both these functions of deoxycholic acid are not recognized in traditional
western medicine till now. Sometimes DCA is even supposed to be
a harmless but useless “mistake of the nature”, a senseless remainder
of evolution. Therefore the most important use of deoxycholic acid
in medical areas is the application as a choleretic or in nutrition
as an emulsifier. Both as well because of its harmlessness and good
physiological tolerance.
But nowadays even in industrial nations we start to realize, that
the role of DCA in our body is much bigger. It has to be emphasized
that many cultures use naturopathic medicine based on herbs which
contain natural deoxycholic acid to cure exactly the diseases you
will find on the indication list on this site. The Chinese people
for example use for possibly thousands of years a naturopathic medicament
called Niuhuang
(herb extract of schisandra chinensis) to heal inflammations and
immune deficiency. The latest findings show, that DCA is the main
component in this traditional medicine. In Poland doctors use a
special mushroom to defeat cancer – and its main constituent is
a substance chemically very close to DCA.
All theses findings point to the function of deoxycholic acid as
a main immunostimulator. We have to emphasize the fact, that all
the information cited on this site is merely based on straight scientific
findings in interdisciplinary research in biology, chemistry and
medicine. Most of the facts were published in the meanwhile, and
many are verified through medical experiments. The information you
read here is in practical use for decades already, but in a silent
way.
The role of DCA in our immune defence
DCA is a substance that soaks all tissues of a healthy human body.
On its health patrol DCA stays in a physiologically inactive form.
But when it stumbles over a local inflammation focus or a tumour
(the blood around both of them is slightly more sour), it changes
its structure to a physiologically highly active form, and forces
a very intense immunity response. The immune reaction activated
by DCA is therefore local, specific and strong.
The part of the immune system DCA works with
is the so called unspecific immune system, mainly dominated by the
macrophages – the biggest immune cells we own. This system is the
task force with the duty to build up a first defence wall towards
incoming infections. Scientific research focused the last decades
on the specific immune system (carried by the lymphocytes, the antibodies
and so on), with the idea to develop new vaccinations for dangerous
diseases and similar tasks. But being mainly focused on this part
of our immunity, the research did not discover this initial defence
mechanism caused by DCA.
Another thing important to know is the steroid-like chemical structure
of deoxycholic acid, because DCA works as an active hormone of our
steroid system. It docks on the receptors of our autonomic nervous
system, and behaves competitive to our corticoidal hormone group
and to some other hormones as many sexual hormones. Supplementary
to its role in immunity DCA has harmonizing effects on the autonomic
nervous system, to be felt in many cases as a regulation of the
bowel movement, normalisation of blood pressure, relief of physiological
stress-symptoms and so on. DCA helps the body to slide into a state
of recovery that is necessary for an effective and fast immune defence.
According to hundreds of results there is one thing that is known
for sure by now. Only with a sufficiently high concentration of
DCA in our tissues, an enough stable first immune defence can be
built up. This is one of the main keys to a robust constitution.
If we have a good health in that sense, many diseases as herpes
or cancer have no chance to develop. But if the level of DCA drops
below a minimum – and that is a fact for many people in industrial
nations – we start to be prone to all kinds of infections, that
normally would be easily fought by our immune system.
Stages of immune deficiency (DCA-avitaminosis)
So once again: The lower our natural DCA-level
is, the more we are prone to all kinds of specific infections. We
can observe different stages of a lack of DCA, which we also describe
as the stages of a DCA-avitaminosis. The stages can be verified
from everybody, and this way it is possible to draw conclusions
on the condition of our unspecific immune system.
Stage1: A hindered DCA circulation causes
disease symptoms of the autonomic nervous system
At this first stage of a not perfectly functioning DCA system
we find disturbances that we (people in industrial nations) don’t
even recognize as disorders – we misjudge them as inevitable weaknesses
of our imperfect bodies. In this category we find all the symptoms
that are based on single sided over-stimulation of the autonomic
nervous system from to the DCA system antagonistic hormones (esp.
corticoids). In this case the symptoms are high blood pressure,
problems with blood circulation, insomnia, irritability and different
problems with digestion as irregular bowel.
Stage 2: A slight DCA-avitaminosis leads
to poor health
At this second stage we find a more serious disturbance of the DCA
circulation or even a slightly lowered DCA production. Our immune
defence is still good enough to fight severe diseases, but it is
already too weak to compete up with the small everyday illnesses,
that we love to suppress with palliative medicaments (no cure, just
a repression on the symptom level). Examples would be diseases accompanied
by fever, long term colds, acne, prolonged wound healing or warts.
Stage 3: An obvious DCA-avitaminosis
leads to manifest diseases
At this stage our body produces definitely too small amounts
of DCA. We get prone to diseases that are too obvious and painful
to repress them, as they keep us from functioning in everyday life.
In this category we find viral caused inflammation diseases as herpes
or chickenpox as well as bacteria caused inflammations like otitis,
sinusitis or infections of the urinal tract and neuralgias.
Stage 4: Severe DCA-avitaminosis leads
to severe diseases
In this category we find diseases we probably would not get
with an at least halfway stable unspecific immune system – only
if being exposed to extreme environmental toxins or a high dose
(or highly infectious) causative agent. Often we can avoid these
illnesses just with a basic knowledge about our immune system. Here
we find many autoimmune diseases, chronic states, cancer and possibly
AIDS.
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